Hemp Inventory Information – International Hemp Group (CSE: GHG) Pronounces Execution of Binding LOI with Apollon Formularies PLC

Vancouver, British Columbia – January 11, 2023 (Newsfile Corp.) ( Newswire) GLOBAL HEMP GROUP INC. (CSE: GHG) (OTC Pink: GBHPF) (FSE: GHG) (“GHG” or the “Firm”) is happy to announce that it has executed a binding Letter of Intent with Apollon Formularies Plc – (AQSE: APOL) (“Apollon”) (the “LOI”), a UK-based worldwide pharmaceutical firm creating most cancers remedies from pure biologics, together with medical hashish, useful mushrooms, psychedelic mushrooms and mixtures of those compounds, which to this point have proven profitable impartial, third-party leads to pre-clinical testing. Apollon makes use of a synthetic intelligence-based drug discovery platform.

Underneath the phrases of the binding LOI dated January 9, 2023, GHG will purchase the unique perpetual license for North America (particularly, the USA, Canada and Mexico) to sure Apollon Mental Property and proprietary expertise, together with, however not restricted to, 4 key patents as described beneath together with any continuations, divisionals, and continuations-in-part, together with any and all related preclinical and medical information regarding the patents and proprietary expertise (the “IP”).

The Firm has additionally been granted a 60-day choice to conduct due diligence, following which GHG might train its possibility to amass the whole thing of Apollon’s international property.

Deal Phrases for the Mental Property

GHG can pay a complete of US$250,000 (C$341,000) in two distinct tranches and concern Apollon 10 million frequent shares of GHG at a deemed worth of C$0.015 per share, for complete consideration of C$491,000. The Firm may even pay Apollon ongoing licensing charges regarding the IP, starting the quarter following when any licensing and sub-licensing revenues are generated. All securities issued on this transaction are topic to a four-month plus a day maintain interval from the date of issuance in accordance with relevant securities legal guidelines. GHG can pay a finder’s price to Twilight Capital Inc. or such different affiliate, designee, or affiliate, representing 5 p.c (5%) of the worth of all the Transaction between GHG and Apollon (the “Finder’s Payment”).

Mental Property – Patent Info and Impartial Check Knowledge Being Licensed

GHG will purchase the unique perpetual license to the next patents (together with any continuations, divisional and continuations-in-part) and any related preclinical and medical information regarding the patents. The patents are registered beneath the Worldwide Patent System (PCT) and are additionally registered in Jamaica. This unique perpetual license will cowl Canada, the USA and Mexico, for the 4 patents beneath and all related supporting information:

  • Compositions and Strategies for Remedy of Cancers;
  • Compositions and Strategies for Remedy of Irritation;
  • Strategies for Remedy of Human Cancers Utilizing Hashish Compositions;
  • Strategies for Remedy of Human Cancers Utilizing Mushroom Compositions;
  • BIOENSIS Preclinical Knowledge reflecting impartial 3D cell tradition testing of hashish and mushroom formulations included within the patent functions.

These patents embrace claims to the remedies of cancers and inflammatory situations utilizing pure biologics together with compounds in medical hashish, useful mushrooms, psychedelic mushrooms and mixtures of those compounds which were proven in impartial, third-party preclinical 3D cell tradition testing to kill most cancers cells by way of direct cytotoxicity and immune stimulated cytotoxicity with nice success and excessive efficacy. Underneath the Unique License Settlement, GHG could have the suitable to sublicense this mental property to legally licensed producers in the USA (state by state the place medicinal hashish is authorized), Canada and Mexico, which permits the chance to generate important near-term sublicensing income in these three nations.

As a way to help GHG in monetizing the IP into an ongoing income stream, the Firm has engaged Dr. Stephen D. Barnhill, creator of the IP and Chairman & CEO of Apollon, as Particular Medical Advisor (“SMA”) to the Firm. Dr. Barnhill will probably be issued a one-time fee of 10 million frequent shares of GHG at a deemed worth of $0.015 per share for his ongoing engagement as SMA. The holding interval for these shares will probably be 4 months and in the future, calculated from the date of issuance.

Dr. Stephen D. Barnhill, MD is presently the Chairman & CEO of Apollon Formularies, Plc (London, UK) (AQSE: APOL), Chairman and CEO of Apollon Formularies, Inc. (USA), President and Board Member of Apollon Formularies Jamaica, Ltd. (Jamaica), and Chairman and CEO of Doc’s Place Worldwide, Inc.

Dr. Stephen D. Barnhill, MD

Dr. Barnhill is a Medical Physician specializing in Cannabinoid and Mycomedicinal Therapeutics, Drug Discovery and Synthetic Intelligence, and has accomplished a Scientific Fellowship in Laboratory Drugs (Scientific Pathology) on the Medical College of South Carolina (MUSC).

Beforehand, Dr. Barnhill was Founder, Chairman and CEO of each personal and public corporations, together with Founder, Chairman, and CEO of BCL laboratories, LLC with operations in southeastern US, which was acquired by Corning-MetPath now Quest Diagnostics, the most important medical laboratory on the earth. After the acquisition, he served as a Medical Director for that Quest Diagnostics location for about 5 years. Dr. Barnhill was Founder, Chairman and CEO of Nationwide Medical Specialty Labs, which was acquired by Horus Therapeutics Inc. (a New York Pharmaceutical Firm) and Chairman and CEO of Well being Discovery Company, a US publicly traded worldwide biotech firm, from inception to profitability.

As CEO, Dr. Barnhill has negotiated and executed offers with many corporations, together with Pfizer, Abbot, Corning-MetPath, Quest Diagnostics, Clarient, LabCorp, NeoGenomics, Bruker and others.

Dr. Barnhill is a pioneer in synthetic intelligence machine studying (sample recognition algorithms) in medication and is an Inventor on greater than 80 worldwide patents, together with neural networks and help vector machines and together with the Hallmark SVM-RFE approach now cited by greater than 10,000 publications. His patents had been a part of the mental property portfolio that received First Place out of 1,600 publicly traded corporations and was awarded the distinguished MICO award from MDB Capital for essentially the most disruptive and market altering mental property portfolio. The neural community patents, with Dr Barnhill as an inventor, had been acquired by Johnson & Johnson.

Dr. Barnhill has been an inventor on patents associated to laboratory developed assessments (LDT’s) and tumor markers, in addition to diagnostic take a look at growth regarding cancers of the prostate, pancreas, breast and ovary, cytogenetics, circulate cytometry, Florescence In Situ Hybridization (FISH), and imaging in digital mammography, funduscopic evaluation of macular degeneration (AMD) and SVM for melanoma detection.

He has revealed many peer-reviewed papers with teachers primarily from MD Anderson Most cancers Middle, Johns Hopkins College Medical Middle, Stanford College Medical Middle and others.

Included in his publications are the next:

• Gene Choice for Most cancers Classification utilizing Assist Vector Machines (Cited by practically 10,000 publications)
– Journal, Machine Studying: Isabelle Guyon, Jason Weston, Stephen Barnhill & Vladimir Vapnik

• A 4-Gene Expression Signature for Prostate Most cancers Cells Consisting of UAP1, PDLIM5, IMPDH2, and HSPD1
– UroToday Worldwide Journal: Isabelle Guyon, Herbert A. Fritsche, Paul Choppa, Li-Ying Yang, Stephen D. Barnhill

• Position of CA125 in Predicting Ovarian Most cancers Survival – a assessment of the epidemiological literature
– Worldwide Journal Organic Markers: R C Bast Jr 1, F J Xu, Y H Yu, S Barnhill, Z Zhang, G B Mills

• Comparability of a Neural Community with Excessive Sensitivity and Specificity to Free/complete Serum PSA for Diagnosing Prostate Most cancers in Males with a PSA < 4.0 ng/mL
– Synthetic Neural Networks in Most cancers Prognosis, Prognosis, and Affected person Administration: T.A. Stamey, S.D. Barnhill, Z. Zhang, C.M. Yemoto, H. Zhang, Ok.R. Madyastha

• Mixture of a number of serum markers utilizing a synthetic neural community to enhance specificity in discriminating malignant from benign pelvic lots.
– Journal, Gynecologic Oncology: Zhang Z, Barnhill SD, Zhang H, Xu FJ, Yu YH, Jacobs I, Woolas RP, Berchuck A, Madyastha KR, and Bast RC

• The power of the ProstAsure™ Index to establish prostate most cancers sufferers with low most cancers volumes and excessive potential for treatment
– Journal, Urology: S. Barnhill, T.A. Stamey, Z. Zhang.

• A neural community (ProstAsureTM) with sensitivity and specificity of 75% in detecting prostate most cancers in males with a PSA < 4.0 ng/ml
– Journal, Urology: TA Stamey, SD Barnhill, Zhen Zhang, KR Madyastha

• Analysis of ProstAsure index within the detection of prostate most cancers: a preliminary report
– Journal, Urology: R J Babaian 1, H A Fritsche, Z Zhang, Ok H Zhang, Ok R Madyastha, SD Barnhill

Dr. Barnhill has been accepted and admitted as a Member or Fellow of the next organizations: the American School of Doctor Inventors, the American School of Worldwide Physicians, the American Medical Affiliation, the American School of Doctor Executives, the American Affiliation of Synthetic Intelligence, the American School of Managed Care Drugs, the Affiliation of Scientific Scientists, the American Society of Modern Drugs and Surgical procedure, the American Society of Regulation, Drugs and Ethics, the Southern Medical Society, the American Federation for Scientific Analysis, the Nationwide Federation of Catholic Physicians and the Society of Hashish Clinicians.

For added info on Dr. Barnhill, please go to the Firm’s web site

Phrases of the Choice to Purchase the Complete Property of Apollon

The LOI supplies for a due diligence interval, presently set at 60 days, throughout which GHG and Apollon might collect additional details about one another’s enterprise and funds. If each events are glad with the outcomes of the due diligence, GHG could have the unique possibility to amass all of the property of Apollon apart from money, money equivalents, and receivables, for a fee of 771,191,266 GHG frequent shares at a deemed worth of $0.015 per GHG frequent share, for complete consideration of C$11,567,869. All securities which can be issued regarding this portion of the transaction will probably be topic to a minimal of four-month plus a day maintain interval from the date of issuance and some other customary delayed launch escrow provisions customary for these sort of transactions in accordance with relevant securities legal guidelines. Within the occasion that GHG workout routines this feature to amass the property of Apollon, the Firm will ask shareholders to think about a share consolidation on a foundation of 5 outdated for 1 new share, and the proposed transaction can be thought-about a basic change for the Firm, per CSE Coverage 8. GHG can pay a finder’s price to Twilight Capital Inc. or such different affiliate, designee, or affiliate, representing 5 p.c (5%) of the worth of all the Transaction between GHG and Apollon (the “Finder’s Payment“). The Finder’s Payment regarding the Asset Acquisition portion of the transaction, if concluded, will probably be payable both in money, GHG Shares or a mix of each.

Apollon Formularies Plc Property that will probably be Acquired on Train of Choice:
• 8 patent functions (4 PCT; 4 Jamaica).

• BIOENSIS Preclinical information.

• The correct to amass 49% Fairness in Apollon Formularies Jamaica, Ltd. (“Apollon Jamaica”) with approval of the Jamaican Hashish Licensing Authority (“CLA”).

• 95% internet income from all operations in Apollon Jamaica, Ltd.

Apollon Formularies Jamaica, Ltd. Property

• CLA Medical Hashish Licenses (Processing, Retail Therapeutic, Analysis & Growth) and all tools required to carry out beneath the licenses. Licenses permit import and export of merchandise globally the place legally allowed.

• The Medical Hashish R&D license permits the Firm to carry out human medical trials with approval of the Jamaican Ministry of Well being.

• Worldwide Most cancers and Persistent Ache Institute (totally medically outfitted and furnished).

• Management of CITIVA Jamaica (College location and Affiliation). Consists of CLA Cultivation License which permits import and export of merchandise globally the place legally allowed. Absolutely outfitted and furnished. GMP approval pending ultimate inspection.

• Medical hashish stock: approximate retail worth US$350,000 (unaudited figures).

• A signed processing settlement for a hemp farming group in Jamaica. Apollon will course of, for a price, the hemp cultivated into CBD oil for international export. It’s anticipated that the farming group could have a number of crops per yr accessible for processing.

• Contract to run medical trials on the Apollon’s facility for a U.S. biotherapeutics firm on a cost-plus foundation.

• Therapeutic Dispensary (totally outfitted and furnished).

• Processing Laboratory (totally outfitted and furnished).

• Analysis and Growth Facility (totally outfitted and furnished).

In mild of Apollon Jamaica’s important Jamaican operations, Apollon is one in every of only a few pure biologic drug growth corporations globally that may be a publicly traded firm, legally licensed to work with full spectrum excessive THC hashish, useful mushrooms and psychedelic mushroom formulations and mixtures of those compounds in a completely licensed and authorized atmosphere that may carry out drug discovery, execute pre-clinical testing, carry out human medical trials, present speedy direct human availability of those remedies by doctor prescription, has an Worldwide Most cancers and Persistent Ache Institute, and is accepted to export our merchandise globally the place legally allowed.

International clients, together with potential companions like Large Pharma, looking for pure biologic merchandise and partnerships can look to corporations like Apollon that can have patent protected formulations, validated by pre-clinical and human medical trial information, reasonably than corporations with random medical hashish and mushroom primarily based merchandise with out this stage of scientific rigor and mental property safety.

The Unique License Settlement with GHG permits these Jamaican developed formulations to be sublicensed and manufactured in the USA, Canada and Mexico the place legally allowed.

The power to undertake drug discovery together with human software and therapy is the funding framework Apollon affords. This framework permits Apollon to gather medical information shortly and precisely on their formulations from real-life remedies at their services by way of each in-patient and outpatient care. Apollon advises that they anticipate the variety of sufferers receiving therapy at their services in 2023 to develop considerably. In addition they anticipate a considerable marketplace for international export of Apollon’s pure biologics and international sublicensing of their mental property formulations.

Stephen D. Barnhill, MD, Chairman and CEO of Apollon said, “I’m extraordinarily happy that GHG has the arrogance in Apollon’s mental property, together with pure biologic formulations using medical hashish, useful mushrooms, psychedelic mushrooms and mixtures of those compounds collectively, to safe an Unique License to offer these formulations, beneath particular person sublicensing agreements, to authorized producers in the USA, Canada and Mexico. This partnership permits Apollon formulations to be made accessible to sufferers in all of North America, which is the most important market globally for these pure remedies.” Dr. Barnhill continued, “I consider that Apollon’s patents, defending the distinctive mixtures of medical hashish compounds mixed with useful and psychedelic mushroom compounds, which have been proven to extend the therapeutic efficacy of those compounds when used collectively vs individually, characterize the way forward for pure mixture therapeutics”.

“I want to take this chance to welcome Dr. Barnhill to the GHG staff as Particular Medical Advisor. Along with being a profitable personal and public firm CEO, he has had a formidable medical profession with important accomplishments, together with being an inventor on greater than 80 award-winning worldwide patents primarily associated to synthetic intelligence-based discovery in most cancers diagnostics and therapeutics. Dr. Barnhill can be the inventor of the Apollon patents, that are included within the GHG Unique Perpetual North American License (United States, Canada and Mexico) of Apollon’s Mental Property, which will probably be an amazing addition to the prevailing IP that the Firm is creating by way of its R&D division”, commented Curt Huber, President & CEO of International Hemp Group. “I really stay up for working with Stephen as we embark on instantly monetizing the distinctive IP we’re licensing for North America on this transaction, as Apollon, as an organization listed on the Aquis Alternate, was unable to enter these markets attributable to jurisdictional constraints. For these similar causes, U.S. buyers had been unable to spend money on Apollon, however will now have the ability to think about funding alternatives on this unbelievable and distinctive mental property by way of GHG.”

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About International Hemp Group Inc.

International Hemp Group Inc. (CSE: GHG) (OTCQB: GBHPF) (FSE: GHG) is concentrated on a executing a multi-phased technique to grow to be a frontrunner within the industrial hemp business in the USA. The Firm is headquartered in Vancouver, British Columbia. The present section of the technique focuses on the event of “sustainable” and “inexperienced” value-added industrial hemp merchandise using the processing of the whole thing of the hemp plant for multi-merchantable functions, as will probably be showcased on the Colorado Hemp Agro-Industrial Zone (HAIZ) venture in Hayden Colorado.

To additional help and innovate the HAIZ, International Hemp Group has established a Analysis and Growth Division to actively pursue the event of Mental Property that may be patented for implementation at its tasks and past. The Division is led by Prof. Víctor M. Castaño, Ph.D.-from the Nationwide Autonomous College of Mexico (UNAM), a extremely acknowledged chief in areas of utilized science and expertise. The R&D staff brings an incredible wealth of information and expertise in a number of disciplines and can initially give attention to growth of Environmentally Pleasant Building Supplies, Nanofertilizers and Enhanced Extraction from Hemp.

For Additional Info Contact International Hemp Group

Curt Huber, President
Tel: 778-726-2900

Cautionary Word Concerning Ahead Trying Statements

Sure info set forth on this information launch might include forward-looking statements that contain substantial identified and unknown dangers and uncertainties. These forward-looking statements are topic to quite a few dangers and uncertainties, sure of that are past the management of International Hemp Group Inc., together with, however not restricted to, the impression of common financial situations, business situations, volatility of commodity costs, foreign money fluctuations, dependence upon regulatory approvals, the supply of future financing and exploration danger, and the legality of hashish and hemp. Readers are cautioned that the assumptions used within the preparation of such info, though thought-about cheap on the time of preparation, might show to be imprecise and, as such, undue reliance shouldn’t be positioned on forward-looking statements. Besides as required by regulation, International Hemp Group Inc. disclaims any intention and assumes no obligation to replace or revise any forward-looking statements to replicate precise outcomes, whether or not on account of new info, future occasions, adjustments in assumptions, adjustments in elements affecting such forward-looking statements or in any other case.

The CSE has not reviewed and doesn’t settle for accountability for the adequacy or accuracy of this launch.

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